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Cedara I-Response™Providing Solutions for Clinical Trials and Oncology
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Overview
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Cedara I-Response supports multiple workflows targeted at pharmaceutical companies and image core labs involved in drug development, clinical trials and research as well as Oncology companies evaluating therapy response over multiple time-points.
Functional Diffusion Mapping (fDM) Workflow
Cedara I-Response provides the patented technology of functional Diffusion Mapping (fDM). Based on the landmark work of Dr. Brian Ross PHD at the University of Michigan, this method allows health care professionals to visualize changes in tumor tissue resulting from cellular and metabolic mechanisms. Functional Diffusion Mapping has the potential to precisely monitor the early impact of anti-cancer drugs and radiation therapy. Cedara I-Response provides radiologists, oncologists, researchers and other health care professionals with a sophisticated tool that collects tumor information at both the functional and anatomical level.
Functional Diffusion Mapping (fDM) Toolkit
Support for fDM Analysis is also provided as a toolkit which can be integrated into third-party applications. The fDM Toolkit provides support for creation of Apparent Diffusion Coefficient (ADC) images along with comparison of multiple ADC timepoints. Volumetric measurements and pixel-wise comparisons on ADC images are provided.
PET Workflow
The PET workflow extends the fDM workflow to allow users to compare changes in PET data by comparing SUV values at the pixel level across multiple time-points including standard volumetric measurements.
Lesion Workflow
Standard RECIST and WHO measurements are supported along with volumetric analysis. Industry leading segmentation and registration tools assist in providing consistent, accurate measurements over multiple time-points.
PET-CT Workflow
The PET-CT workflow extends the lesion workflow to allow PET-CT studies to be reviewed over multiple time-points. PET-CT registration and fusion, SUV and isocontour analysis as well as advanced segmentation tools are included in this new PET-CT workflow.
Clinical Trials Support
Cedara I-Response provides a set of features tailored to the Clinical Trials industry such as:
Rules that prevent users from creating measurements that do not fit with a trial, e.g., drawing measurements within specified dimensions only.
Support for double blind reading using role profiles which define a user’s access to measurements on the system.
Plug-In Support
Cedara I-Response is available as a standalone application, or can be tightly integrated into Cedara I-Reach™, or to an existing solution using the Cedara Clinical Control Center (C4) platform. Cedara I-Response may also provide a platform for customers that wish to integrate their solutions into an existing application in order to take advantage of the wide array of tools provided by Cedara I-Response.
DICOM Integration
Cedara I-Response can be easily integrated into PACS and other environments through standard DICOM communication including:
Launch via DICOM Part 10 files.
Output via DICOM Secondary Capture.
Automated generation of reports with all measurements in industry standard document formats.
Import and display of DICOM RT structure sets to support radiation therapy workflow.
Output measurements to a file for import into existing data repositories
